SMARTHANDLE’s dexterity, reconfiguration and reasoning enabling technologies will be validated and will demonstrate their advances through three real-life manufacturing scenarios. Those originate from Metal (ALUMIL), Consumer goods (MENICON) and Automotive tier-one supply (ABEE) industrial sectors. These use cases have been selected for covering a wide spectrum of dexterous handling operations. In overall, the project’s outcomes will tackle handling challenges for small to large sized parts, made from rigid or deformable materials, presenting simple or sophisticated geometries that require conventional or specialized handling treatments.